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Coconut Oil, Butter and Olive Oil, Ranked by the Evidence on Inflammation

Is coconut oil inflammatory or anti-inflammatory? Trials that fed people all three fats found the inflammation numbers tied. Cholesterol broke the tie.

Evidence: Not supported
Four adults of different ages chat around a kitchen island as one tosses a big wooden bowl of salad beside trays of vegetable-topped toasts.“Coconut Oil Lowers Inflammation”Evidence: Not supported
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The 30-second version

5

trials measured CRP when people ate coconut oil instead of other cooking oils. Pooled, coconut oil did not change it.

Source 1
10.47

mg/dL: how much coconut oil raised LDL cholesterol compared with non-tropical plant oils, across 16 trials.

Source 1
6

inflammation markers, including hsCRP and IL-6, showed no difference when 45 adults ate coconut oil, palm olein and olive oil diets.

Source 2
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The short answer

Neither, as far as trials can tell. In a 2020 meta-analysis, coconut oil did not change CRP, a blood marker of inflammation, compared with other cooking oils in 5 trials. It did raise LDL cholesterol by 10.47 mg/dL across 16 trials. Butter raised LDL even more, and olive oil came out on top.

Side by side

In the summer of 2017, 94 volunteers aged 50 to 75 in Cambridgeshire, England, were each randomly given one fat to eat every day for 4 weeks. It was 50 g of extra virgin coconut oil, unsalted butter or extra virgin olive oil. They could cook with it or simply eat it on its own.

Few studies line these fats up so directly. So we pulled every head-to-head result from our sources into one table. Two terms first. CRP (C-reactive protein) is a protein in the blood that rises when the body is inflamed. LDL is the cholesterol that builds up in artery walls.

MatchupInflammation markersLDL cholesterolStudy type
Coconut oil vs non-tropical plant oilsCRP: no clear change (5 trials)Up 10.47 mg/dL on coconut oil (16 trials)2020 meta-analysis
Coconut oil vs palm olein vs virgin olive oilNo difference in any of 6 markers, including hsCRP and IL-6All fasting blood fat measures lower on olive oil than on coconut oilCrossover trial, 45 adults, 5 weeks per diet, 2011
Coconut oil vs butter vs olive oil, 50 g a dayCRP was measured, but the summary gives no result for itButter up 0.42 mmol/L vs coconut oil; coconut oil and olive oil about equalRandomized trial, 94 adults aged 50 to 75, 4 weeks, 2018
Butter vs refined olive oilhsCRP: no differenceHigher total and LDL cholesterol on butterCrossover trial, 47 adults, 5 weeks per diet, 2015
Olive oil vs a mix of control dietsCRP down 0.64 mg/L (15 trials); IL-6 down 0.29 (7 trials)Not pooled in this review2015 meta-analysis of 30 trials, 3,106 people

Read down the inflammation column. In every direct matchup, it says the same thing. Now read the LDL column, where the three fats fall into a clear order.

Is coconut oil inflammatory or anti-inflammatory?

The "anti-inflammatory" idea mostly rests on medium-chain fats. Coconut oil got popular because people credit these fats with health perks. But its main fat, lauric acid, may act like both a medium-chain and a long-chain fat in the body. A 2019 review warned that tests of pure medium-chain fats don't apply straight to coconut oil. Many claims, it said, rest on animal studies, lab-dish studies or those pure fats.

In every direct matchup, coconut oil, butter and olive oil tied on inflammation markers. LDL cholesterol broke the tie.From a 2011 randomized trial in Am J Clin Nutr

So what happens when people actually eat it? In a 2011 trial in Malaysia, 45 healthy adults ate three diets for 5 weeks each, cooked with palm olein, coconut oil or virgin olive oil. None of the 6 inflammation markers moved differently between the diets. That list included hsCRP, IL-6 (a signal immune cells use to call up inflammation) and TNF-alpha.

The 2020 meta-analysis, which pools the results of many trials, found the same. In the 5 trials that measured CRP, coconut oil did not change it compared with non-tropical plant oils.

The opposite worry gets the same answer. Coconut oil is high in saturated fat. Yet in these trials it did not push inflammation markers above what the other oils did. On this evidence, coconut oil is neither.

Where they are the same

Butter faced olive oil in a 2015 crossover trial, where each person tried both. The 47 healthy adults had an average age of 40.4. Each swapped part of their usual diet for butter for 5 weeks, then for refined olive oil for 5 weeks. Their hsCRP did not differ between the two. Neither did their insulin or blood sugar.

That makes three direct matchups with the same result: no fat in this trio beat another on inflammation.

Then why does olive oil have a CRP drop in the table? That review pooled 30 trials of olive oil against all kinds of control diets, often as part of a Mediterranean-style eating plan. The trials were set up in very different ways, so the authors urged a careful reading. It's a real signal. It just was not measured against butter or coconut oil.

Where they differ

Cholesterol is the split, and it is not small. In the 2018 Cambridgeshire trial, butter raised LDL by 0.42 mmol/L more than coconut oil, and by 0.38 mmol/L more than olive oil. Coconut oil and olive oil came out about equal on LDL. Coconut oil also raised HDL, the "good" cholesterol, more than either one.

One 4-week trial is a narrow window, though. The 16-trial meta-analysis gives a wider view: coconut oil raised LDL by 10.47 mg/dL and HDL by 4.00 mg/dL compared with non-tropical plant oils, and the LDL rise held up when weaker trials were left out. A 2016 review of 8 trials and 13 observational studies saw the same order. Coconut oil raised total and LDL cholesterol more than unsaturated plant oils, but less than butter.

A 2020 meta-analysis of 12 studies drew the same line. Compared with animal fats, coconut oil lowered LDL; compared with plant oils, it raised it. Virgin coconut oil had the better cholesterol numbers of the coconut oils.

What about coconut oil on your skin?

That is a different question from eating it. A 2019 review found limited but consistent evidence for using coconut oil on the skin in atopic dermatitis, a common type of eczema. It says nothing about what eating coconut oil does inside your body.

The tiebreaker

With inflammation a draw, LDL cholesterol decides it. The American Heart Association ties LDL directly to atherosclerosis, the buildup that narrows arteries. In its 2017 advisory, trials that cut saturated fat and replaced it with polyunsaturated vegetable oil lowered heart disease by about 30%. Swapping saturated fat for refined carbs and sugar did not.

You may have heard that people in the tropics eat plenty of coconut and do fine. In traditional diets, eating coconut flesh or squeezed coconut was not linked to heart problems. But those diets and lives differ so much from a typical Western diet that the finding does not carry over. Even the trial authors who found coconut oil close to olive oil said their results do not change the advice to cut back on saturated fat.

So here is the ranking. Olive oil first: tied on inflammation, best on LDL, and the only one with a pooled CRP drop. Coconut oil second. Butter third.

Which to pick

Tick what you'll try this week. Your picks stay on this device.

Talk to your doctor first if

you have high LDL cholesterol, heart disease or a family history of very high cholesterol; you take a medicine for cholesterol (keep taking it as prescribed and ask before changing it); or you want to put coconut oil on a child's eczema.

Will you try it?

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How this article was made

Researched and written from 9 peer-reviewed papers. Our automated check matched every claim against the exact words of its source, confirmed every paper exists in PubMed, and found none retracted. Checked November 4, 2026. Not individually reviewed by a doctor. Photos are illustrative; the people in them are not patients or readers.

Grades run Strong, Moderate, Emerging, Early and Not supported, and the grade decides the words we may use. How we grade evidence · Medical disclaimer

Sources

  1. Meta-analysisThe Effect of Coconut Oil Consumption on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Clinical Trials.Neelakantan N, Seah JYH, van Dam RM Circulation, 2020.PubMedFull paper
  2. Randomized trialDiets high in palmitic acid (16:0), lauric and myristic acids (12:0 + 14:0), or oleic acid (18:1) do not alter postprandial or fasting plasma homocysteine and inflammatory markers in healthy Malaysian adults.Voon PT, Ng TK, Lee VK et al. Am J Clin Nutr, 2011.PubMedFull paper
  3. Randomized trialRandomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women.Khaw KT, Sharp SJ, Finikarides L et al. BMJ Open, 2018.PubMedFull paper
  4. Randomized trialButter increased total and LDL cholesterol compared with olive oil but resulted in higher HDL cholesterol compared with a habitual diet.Engel S, Tholstrup T Am J Clin Nutr, 2015.PubMedFull paper
  5. Meta-analysisEffects of Olive Oil on Markers of Inflammation and Endothelial Function-A Systematic Review and Meta-Analysis.Schwingshackl L, Christoph M, Hoffmann G Nutrients, 2015.PubMedFull paper
  6. Meta-analysisImpact of coconut oil consumption on cardiovascular health: a systematic review and meta-analysis.Teng M, Zhao YJ, Khoo AL et al. Nutr Rev, 2020.PubMedFull paper
  7. ReviewCoconut oil consumption and cardiovascular risk factors in humans.Eyres L, Eyres MF, Chisholm A et al. Nutr Rev, 2016.PubMedFull paper
  8. ReviewHealth Effects of Coconut Oil-A Narrative Review of Current Evidence.Wallace TC J Am Coll Nutr, 2019.PubMedFull paper
  9. ReviewDietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association.Sacks FM, Lichtenstein AH, Wu JHY et al. Circulation, 2017.PubMedFull paper
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